Cubosomes are discrete, sub-micron, nanostructured particles of bicontinuous cubic liquid
crystalline phase
viscous material that has a unique structure at the nanometer scale
assembly of liquid crystalline particles of certain surfactants when mixed with water and a
microstructure at a certain ratio.
Cubosomes offer a large surface area, low viscosity and can exist at almost any dilution level.
They have high heat stability and are capable of carrying hydrophilic and hydrophobic
molecules
release through functionalisation, they are an attractive choice for cosmetic applications as
well as for drug delivery. However, at present cubosomes do not offer controlled release on
their own
A number of companies including L’Oréal
investigating cubosomes for cosmetic applications. Despite this interest, cubosomes have not
yet led to products
up before this type of technology can be applied. The presence of large amounts of water
during cubosome formation makes it difficult to load water soluble actives.46. Bicontinuous cubic liquid crystalline phase is an optically clear, very47. It is formed by the self48. Combined with the low cost of the raw materials and the potential for controlled49. They have also been modified using proteins50,51.52, Nivia53,54,55,56 and Procter and Gamble are57. The methods of formation must be efficient and cost-effective for scale
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