TABLET COATING
FIRST OF ALL DO YOU HAVE A DOUBT, WHY TO COAT TABLETS?
Coating is performed for the following reasons:
1. Providing controlled, continuous release or reduce the frequency of drug dosing
2. Maintaining physical or chemical drug integrity
3. Enhancing product acceptance and appearance
4. Protects the tablet (or the capsule contents) from stomach acids
5. Protects the stomach lining from aggressive drugs such as enteric coated aspirin
6. Provides a delayed release of the medication
7.Maintains shape of the tablet.
COATING PROCESS DESIGN AND CONTROL:
Tablet coating takes place in a controlled atmosphere inside a perforated rotating drum. Angled baffles fitted into the drum and air flow inside the drum provide means of mixing the tablet bed. As a result, the tablets are lifted and turned from the sides into the centre of the drum, exposing each tablet surface to an even amount of deposited/sprayed coating.
The liquid spray coating is then dried onto the tablets by heated air drawn through the tablet bed from an inlet fan. The air flow is regulated for temperature and volume to provide controlled drying and extracting rates, and at the same time, maintaining the drum pressure slightly negative relative to the room in order to provide a completely isolated process atmosphere for the operator.
Tablet coating equipment may include spray guns, coating pan, polishing pans, solution tanks, blenders and mixers, homogenizers, mills, peristaltic pumps, fans, steam jackets, exhaust and heating pipes, scales and filters. The coating process is usually a batch driven task consisting of the following phases:
• Batch identification and Recipe selection (film or sugar coating)
• Loading/Dispensing (accurate dosing of all required raw materials)
• Warming
• Spraying (application and rolling are carried out simultaneously)
• Drying
• Cooling
• Unloading
There are several types of tablet coating
http://www.pharmainfo.net/kamrutha/tablet-coating
FIRST OF ALL DO YOU HAVE A DOUBT, WHY TO COAT TABLETS?
Coating is performed for the following reasons:
1. Providing controlled, continuous release or reduce the frequency of drug dosing
2. Maintaining physical or chemical drug integrity
3. Enhancing product acceptance and appearance
4. Protects the tablet (or the capsule contents) from stomach acids
5. Protects the stomach lining from aggressive drugs such as enteric coated aspirin
6. Provides a delayed release of the medication
7.Maintains shape of the tablet.
COATING PROCESS DESIGN AND CONTROL:
Tablet coating takes place in a controlled atmosphere inside a perforated rotating drum. Angled baffles fitted into the drum and air flow inside the drum provide means of mixing the tablet bed. As a result, the tablets are lifted and turned from the sides into the centre of the drum, exposing each tablet surface to an even amount of deposited/sprayed coating.
The liquid spray coating is then dried onto the tablets by heated air drawn through the tablet bed from an inlet fan. The air flow is regulated for temperature and volume to provide controlled drying and extracting rates, and at the same time, maintaining the drum pressure slightly negative relative to the room in order to provide a completely isolated process atmosphere for the operator.
Tablet coating equipment may include spray guns, coating pan, polishing pans, solution tanks, blenders and mixers, homogenizers, mills, peristaltic pumps, fans, steam jackets, exhaust and heating pipes, scales and filters. The coating process is usually a batch driven task consisting of the following phases:
• Batch identification and Recipe selection (film or sugar coating)
• Loading/Dispensing (accurate dosing of all required raw materials)
• Warming
• Spraying (application and rolling are carried out simultaneously)
• Drying
• Cooling
• Unloading
There are several types of tablet coating
http://www.pharmainfo.net/kamrutha/tablet-coating
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